Vampires: wooden stake to the heart or cut off their head, drown them in sunlight. Very strong and fast, pretty clever. More likely to be alone than the wolves but have their groups too. Sometimes they sleep together during the day, and you bust in and find them and they're weak from the sun and easier to take out a load of them. Werewolf blood ain't a poison to them.
Wolves: pack hunting, dead strong, vicious. Dunno about weaknesses but where I'm from: silver, gbh. Grievous bodily harm. They can heal from a lot but if you hurt them enough, they ain't immortal. Beheading, I reckon. They shift all the time.
That's what I know about out there, been hunting every day.
And I won't hunt anybody who's from the hotel even if they're a vampire so if that's keeping anybody from saying they got changed, I think we should all promise you're gonna be safe. It's just those ones out there I'll go after.