Maria was not a touchy feely person, but she didn't pull away when Hades took her hand. While she wasn't exactly at ease with him, that would take time, she trusted him and her own skills enough to allow the familiarity.
"Far be it from me to tell you what to think," she said with a grin of her own. "And if you keep looking at me like that I'm going to have a hard time focusing on where we're going."