Sam will be weirdly glad to see Tony because in 616 he's uh in that coma and all.
He's a little less glad to see Clint because they just have their long weird history where Sam stole Clint's spot on the team that he didn't even want and Clint assassinated Bruce in front of everyone, and like he does get that Clint was doing what Bruce asked, but also he did not buy tickets to that show and would like to complain to management.
I think there was one ridiculous story somewhere that was played for jokes where Loki broken into the mansion for some reason and Sam was in the shower so he turned the water cold. ¯\_(ツ)_/¯ He knows of him, at least.