Brenda: I think it's all just totally random.
Nate: Really?
Brenda: Yeah. We Live, we die, ultimately nothing means anything.
Nate: How can you live like that?
Brenda: I don't know. Sometimes I wake up so fucking empty I wish I'd never been born, but what choice do I have?
(yes, it's old, but i've just been watching it lately)