"Let's go with 'no.'" Dean might be living with a comicbook hero, but he didn't need another one to show the existence of yet another comic reality. Yes, Dean was aware enough to know that Superman and Spider-man weren't in the same reality...right?
"Let's just drink our drinks, and not worry about anyone being who they say they are, think they are, or just are. Let's go with just drinking." Drinking seemed like a good way to go. Plus, it might have been a good way to keep himself from asking something he shouldn't, like was Jean Grey really great in the sack? Red heads could be hot, even if this one could read every single thing that went on in a guy's mind.