If you had Eddie Brock in such a story, that would be a distinct possibility. In fact, it wouldn't even be terribly surprising.
But not Ben Reilly. His moral character may not be as "developed" as Pete's, whatever that means, but it still pretty much includes the same boundaries!!! What the fuck?
If you had a story about someone who was beaten up so bad they'd never walk again, or were in a coma, and there was a question of "Did Ben Reilly do it?" that I could almost sorta buy. But killing a family?
Marc Guggenheim shouldn't be allowed to touch anyone in the Spider-man family.