He didn't acknowledge her, nor did his warriors. To them, this was a sacred thing. They brought the man out and draped him over the altar. The mortal been given drugs so he wouldn't struggle, and he seemed to barely register where he was.
The priest started to chant, holding the obsidian blade over the mortal's chest. When the sun crested just above the horizon, the priest struck and with quick movements brought out the heart. It was done so quickly the heart beat it's last pulses as the mortal gurgled, then died.
Reverently the priest gave the god the heart and without any hesitation Huitzilopotchli took the offering and bit into it. His mouth was covered with blood when he drew back, and only then did he look to Mary and tilt his head, to see what she would do.