Marvel and Amani were friends in high school, and it looks like Amani and Owen were dating when Marvel was busy discovering she was also a he and contracting HIV. He probably got a little bitchy and jealous when they first started going out, but eventually stopped being a twit. Given that they've both been busy in the last decade, they're probably mostly out of touch, but obviously they can fix that. :D
Luka's the kind of person Amani would just kind of know for social reasons, and he's probably participated in some political stuff or charity galas they've been at, and he's a notable part of Stark's science division, what with his cybernetic organs and prosthetics. They probably get along.
They're probably not close or anything, but she definitely knows Jes. I can't imagine that relationship being negative.
She's probably run into Mark a couple times. Fame, etc.
I'm not sure about anyone else, but it's early. XD